Last update: 05.11.12



Welcome to the Doering laboratory in the Department of Molecular Microbiology at Washington University Medical School.

We study the pathogenic fungus Cryptococcus neoformans, which causes serious infections in immunocompromised individuals. We are investigating unique aspects of cryptococcal biology with the dual goals of understanding basic processes and identifying potential drug targets.

The main focus of our work is the dominant virulence factor of C. neoformans, its polysaccharide capsule. We are examining how the capsule is synthesized, regulated, and associates with the cell, using approaches ranging from biochemistry and cell biology to molecular biology and genome analysis; we are also interested in interactions between this fungal pathogen and its host. To learn more please look at our recent papers or contact us by using the buttons to the left.

Click here for a recent job posting for postdoctoral fellows.